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What is the mechanism of action of levothyroxine? Mechanism of action T4 and T3 bind to thyroid receptor proteins in the cell nucleus and cause metabolic effects through the control of DNA transcription and protein synthesis. Like its naturally secreted counterpart, levothyroxine is a chiral compound in the L-form.
What should my thyroid levels be to get pregnant? Thyroid levels Before conception it's currently recommended that your TSH (thyroid stimulating concentration) should ideally be kept in the lower half of the reference range (between 0.5 and 2.5 mU/L) as this has been associated with a lower risk of miscarriage.
When should I take my levothyroxine? Typically, patients are advised to take their levothyroxine first thing in the morning, at least 30 minutes but preferably an hour before eating, on an empty stomach and with only water. The goal is to achieve consistency in taking the medication to avoid fluctuations in thyroid levels and variable control of symptoms.
How long does it take for thyroid medicine to start working? The medication used to treat hypothyroidism is long acting, so in the beginning, it may take weeks before you experience improvement. When you start levothyroxine you won't feel better the next day. You may not feel better in two weeks. But symptoms should start disappearing within a month.
What is the half life of levothyroxine? 7 days
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